Abstract
Various probe configurations were modeled. The resulting fluorescence spectra of a human-skin tissue model were analyzed. The Monte Carlo method implemented in the TracePro software package was used to simulate light propagation in the tissue and optical fiber. The endogenous fluorophores riboflavin and protoporphyrin IX served as fluorescence sources in the skin model, had minimally overlapping emission spectra, and provided fluorescence of human skin when excited by laser radiation at 405 nm. The assumption that the fluorescence signal could be selected according to tissue depth using specific parameters of the fiber optic probes was verified. Model spectra using six configurations of fiber optic probes were obtained for the first time with selective sensing of skin auto fluorescence.
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