Modeling Multivariate Count Time Series Data with a Vector Poisson Log-Normal Additive Model: Applications to Testing Treatment Effects in Single-Case Designs

Abstract

In education and psychology, single-case designs (SCDs) have been used to detect treatment effects using time series data in the presence or absence of intervention. One popular design variant of SCDs is a multiple-baseline design for multiple outcomes, which often collects outcomes with some form of a count. A Poisson model is a natural choice for the count outcome. However, the assumption of the Poisson model that the outcome variable’s mean is equal to its variance is often violated in SCDs, as the variance is often larger than the mean (called overdispersion). In addition, when multiple outcomes are from the same participant, it is likely that they are correlated. In this paper, we present a vector Poisson log-normal additive (V-PLN-A) model to deal with (a) change processes (auto- and cross-correlations and data-driven trend) and (b) correlation and overdispersion in multivariate count time series. A multivariate normal distribution was adapted to account for correlation among multiple outcomes as well as possible overdispersion. The V-PLN-A model was applied to an educational intervention study to test treatment effects. Simulation study results showed that parameter recovery of the V-PLN-A model was satisfactory in a large number of timepoints using Bayesian analysis, and that ignoring change processes and overdispersion led to biased estimates of the treatment effects.