Abstract
Lipoprotein particles are aggregates of fat and protein whose purpose is to transport fats in the aqueous environment of plasma. Tracer kinetic studies and- the mathematical models developed to interpret the resulting data have provided many insights into the physiology and pathophysiology of lipoprotein metabolism. With the advent of better methodologies to quantitate stable isotopes, there has been a resurgence in metabolic studies. This has resulted in a need to restudy all aspects of tracer methodologies applied to lipoprotein metabolic studies. These will be discussed in the context of designing tracer kinetic metabolic studies with particular focus on (i) using radioactive and stable isotopic tracers, (ii) using endogenous and exogenous labeling techniques, and (iii) selecting modeling methodologies.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.