Abstract

Many bacteria species are able to expedite colony expansion through motility of the cells. Clostridium perfringens, the primary cause of lethal gas gangrene, exhibit a unique mode of colony expansion on a substrate surface that, surprisingly, does not depend on motility in single cells. Specifically, daughter cells maintain end-to-end connections after cell division, amounting to long chains of cells that continuously grow as individual cells grow and divide. Such cell growth-driven motility would accelerate as cell divisions increase the number of cells in a chain, and the tip of a long chain can potentially reach a very high speed.

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