Abstract
The model analysis of a bioreactor with two intercalated-spiral sets of hollow fibers with alternated dead ends is presented. Design equations are derived based on a model with two jumped fibers and an approximation of the fluid mechanics with a small fiber radius-to-length ratio. The performance of the bioreactor is simulated with and without cell growth utilizing a segregated radial flow model in the extracapillary space. The pressure modulus, the wall Peclet number, the Thiele modulus, and the Monod constant are used as model parameters. The results can be used to assess the proper choice of fiber permeability, fiber length, fiber spacing, and flow velocity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
