Abstract

Vitamin K is reduced to vitamin KH2 by lipoate in biological systems. To provide a model system for this reaction, we have studied the in vitro reduction of vitamin K by 1,3- propanedithiol. This reaction occurs rapidly in dimethyl sulfoxide (DMSO) at 23°C, demonstrating the validity of this model system. © 1996 John Wiley & Sons, Inc.

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