Abstract
This article discusses various aspects of epilepsy which could be modeled in order to investigate basic mechanisms underlying the component parts of the many human epileptic conditions, and describes types of animal models, including presumed epileptic equivalents, acute experimentally induced seizure models, and chronic experimentally induced epilepsy models. We then consider the application of experimental models to test therapeutic and diagnostic approaches, and to understand the fundamental neuronal mechanisms underlying the many aspects of clinical epilepsy.
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