Abstract
Background: Previous studies have shown that the prognostic significance of ventricular tachycardia (VT) induced by 3 ventricular extrastimuli (VES) is similar to VT induced by 1 or 2 VES in low ejection fraction (EF) patients. But it is unknown that the mode of VT induction is associated with implantable cardioverter defibrillator (ICD) therapy. Methods and Results: We retrospectively investigated 109 consecutive patients with structural heart diseases who received ICD implants. Patients without inducible VTs and hypertrophic cardiomyopathy were excluded from the study. Total of 69 patients were included. They were divided into 2 groups; (A) VTs induced by 1 or 2 VES (n=31), (B) Induced by other stimulation (n=38). There was no difference in EF (33% vs. 36%, P=NS). During a mean follow-up of 47.9±40.2 months, 31 patients (44.9%) received appropriate ICD therapy (shocks or antitachycardia pacing). Twenty-one patients in Group A and 10 in Group B received appropriate ICD therapy (67.7% vs. 26.3%, P=0.001). Conclusion: In this retrospective analysis, mode of VT induction, especially 1 to 2 VES, was a predictor of ICD therapy in low EF patients.
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