Mode of synaptic transmission between vestibular afferents and neurons of the vestibular nucleus in the frog

Abstract

Excitatory postsynaptic potentials (EPSPs) were evoked in vestibular neurons of the isolated frog brainstem by stimulation of the ipsilateral vestibular nerve or by direct intra-axonal activation of single vestibular fibers. Composite as well as single-fiber EPSPs usually displayed two components. A Ca 2+-deficient, Mn 2+-containing solution abolished the delayed chemical components of the EPSPs, but did not affect the short latency responses suggesting a dual (electrical-chemical) mode of transmission between some vestibular afferents and vestibular neurons.