Abstract
A TECHNIQUE has been described by which it is possible to estimate the thyroxine (T4) secretion rate of live fowls (Pipes et al., 1958). This method has made possible study of some of the factors influencing thyroxine secretion rate (TSR) of two lines of New Hampshire chickens developed by El-Ibiary and Shaffner (1950) on the basis of differences in their response to the administration of a goitrogen. Premachandra et al. (1958) reported that the line which showed the greatest enlargement of their thyroid glands caused by thiouracil feeding had mean winter TSR of 1.01 ± 0.47 μg. 1-thyroxine/100 g. body weight/day; whereas, the line which showed minimal enlargement had mean TSR of 2.97 ± 1.43 μg./l00g. body weight/day. It was shown subsequently, that the line with the high TSR declined 58% and the low line 42% during the summer months (Stahl and Turner, 1961). To obtain the potential maximum TSR …
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