MO592: Evolution of Body Composition During a Intradialysis Exercise Program Using Virtual Reality

Abstract

BACKGROUND AND AIMSThere are few follow-up studies on the composition body by bioimpedance in exercise programs in different population. It is necessary to know if the body composition measured by bioimpedance change during a intradialysis exercise program using virtual reality. The aim is to determine evolution of body composition of patients on intradialysis exercise program using virtual reality.METHODThis is a subanalysis in a clinical trial with intradialysis exercise intervention. Intradialysis exercise consists in a video game adapted to dialysis: Treasure hunting. It is a nonimmersive virtual reality game in which the patient must catch some objectives avoiding obstacles by moving the lower limbs. The exercise lasts from 20 to 40 min. Intensity was checked through the rate of perceived exertion. The body composition is determined by multi-frequency stereoscopic bioimpedance . The study started in September 2019 (Baseline) but due to the COVID-19 pandemic it was paused for 1 year and started again in March 2021 (Restart). Body composition was determined basal, at 3th and 6th month in program. This study is funding from Programa Estatal de I + D + i Orientada a los Retos de la Sociedad, del Plan Estatal de Investigación Científica y Técnica y de Innovación 2017–2020 del Gobierno de España.RESULTSThis is an open recruitment study, 49 patients have been recruited as of September 2021, mean (SD) age 72 (13) years, females 18. About 17 patients dropped out (16 of them don’t return after the pandemic start). To date, 32 patients are in exercise program.Baseline N 303-month N 30Restart N 283-month N 28Normal hydration weigh (kg)67.8 (14.2)68.0 (12.6)72.1 (17.5)72.4 (18.3)Body mass index26.2 (5.4)26.4 (5.2)28.5 (6.1)28.6 (6.4)Overhydration (liters)2.1 (1.2)2.1 (1.4)2.0 (1.4)1.8 (1.6)Lean tissue index11.7 (2.9)11.0 (2.8)10.5 (2.5)10.2 (2.4)Fat tissue index13.3 (6.6)14.2 (6.7)16.8 (7.4)17.3 (7.9)Mean (SD)Paired data analysis showed no difference in normohydrated weight, lean tissue index, or overhydration. The fat tissue index increased significantly (P 0.04) during the pause period in the first year of the pandemic. At the time of this communication, only 12 patients have completed 6 months of the program. We await the evolution of all included patients to report results at 6 months.CONCLUSIONThe evolution of body composition measured by bioimpedance during an intradialysis exercise program by virtual reality did not show relevant changes. Considering our results and those of previous studies, it’s possible that bioimpedance is not a very sensitive test to evaluate an intradialysis exercise program in the short to medium term. Longer and larger studies are needed.