MO472: Comparison of the Quality of Life and Survival in Children Undergoing Hemodialysis Versus Peritoneal Dialysis: A Comparative Cross-Sectional Study

Abstract

Abstract BACKGROUND AND AIMS A child with end-stage renal disease (ESRD) hopes for a kidney transplant to avoid dialysis. Despite the recent priority rules for assigning transplants to children. Most of them, due to their young age, the time required to prepare for the transplant, and especially the limited availability of grafts, will go on dialysis. The objective of this study is to compare the quality of life and survival of children with ESRD treated by hemodialysis (HD) and those treated by peritoneal dialysis (PD). METHOD All children with end-stage renal disease under the age of 16 who started dialysis treatment between 2018 and 2021 were included, for a total of 72 children. Data were collected from an HRQOL questionnaire (Health Related Quality of Life ESRD Module questionnaire). RESULTS A total of 72 children on ESRD started dialysis between 2018 and 2021. A total of 62 children on hemodialysis (87.5%) versus 10 children on peritoneal dialysis. The mean age in our study was 10 years ± 8 years, with a 58% female predominance. Causal nephropathy was dominated by malformative uropathy in 36% of cases, indeterminate nephropathy in 24% and lupus in 12.5% ​​of cases. Growth retardation was observed in 49 children in our population (79%) (48 in HD versus 1 in PD P < .001). Residual renal function was preserved in 48.6% of our children with a state of normal extracellular hydration (HD 40%, DP 8%). The mean HD and DP hemoglobin level was 8 mg/dL. The initial GFR was 5 with an average urea level at the start of dialysis of 3 g (3 g for HD and 2 g for children on PD). The evolution was marked by the occurrence of complications in PD (6 peritonitis and 2 infections of emergence of KTT) and HD (arteriovenous fistulae hematoma in 10 children, secondary hyperparathyroidism in 65% of children), 10 children are deceased (1 in PD and 9 in HD). Children on PD have a lower co-morbidity and dialysis initiation is more planned. CONCLUSION PD remains the technique of choice in our context to ensure a better quality of life for children.