Mo1959 Induced JunD Represses Intestinal Epithelial Cell Proliferation by Increasing MicroRNA-29b After Polyamine Depletion

Abstract

G A A b st ra ct s (p<0.05). Conclusions: Pediatric AP patients are kept fasting for extended periods of time and the initial diet is typically clear liquids despite the lack of evidence to support this practice. Tolerance of nutrition continues to be monitored by serum lipase levels even though it is known to correlate poorly with disease severity. Pediatric AP patients with more severe disease are more likely to receive PN and spend longer periods fasting. This occurs despite evidence in adults suggesting that early enteral nutrition is associatedwith improved outcomes in severe AP. Because of this discrepancy, there is a need for further research in pediatric AP regarding the potential benefit of EN and its early institution.