Mo1928 Usefullness of Contrast-Enhanced Ultrasonography to Evaluate a Post Treatment Effect of Radiofrequentry Ablation About Hepatocellular Carcinoma; Comparion With Contrast-Enhanced CT

Abstract

Aim. We assessed the usefulness of post-vascular images on contrast-enhanced ultrasonography (CE-US) in the gross classification of hepatcellular carcinoma (HCC) in comparison with contrast-enhanced CT (CE-CT) findings. Methods. 51 patients with 61 HCCs underwent hepatectomy, and the gross type of HCCwas estimated by CE-US and CE-CT.We assessed the tumor shape by defect images during the post-vascular phase onCE-US using perfluorocarbon microbubbles, whereas the positive enhancement in the arterial phase and wash-out in the equilibrium phase on CE-CT. Patients were divided into two subgroups according to the gross classification: simple nodular type and non-simple nodular type. The capability of each imaging modality to correctly depict tumor shapes was compared. Results. Thirty-nine tumors were macroscopically diagnosed as simple nodule type, 19 tumors as simple nodular type with extranodular growth, and 3 tumors as confluent multinodular type from the resected specimen. The sensitivity and specificity of CE-US to diagnose the non-simple nodule type HCC were 86.4% and 89.7%, while those of CE-CT were 68.2% and 76.9%, respectively. The accuracy was significantly better in CE-US compared with CE-CT (88.5% vs 73.8%; p=0.037). Conclusion. The post-vascular phase image of CE-US is a more reliable tool to evaluate the gross type of HCC than CE-CT and is considered to be essential for the determination of treatment strategy and to estimate the prognosis of HCC patients. The sensitivity, specificity and accuracy of the gross type of HCC on CE-CT and CE-US