Abstract

adenoma in the groups that underwent colonoscopy twice or three times within the previous 5 years, compared with the group that underwent colonoscopy once or less in the low-risk group, and in the increased-risk group were 0.33 [95% confidence interval (CI), 0.14-0.81] and 0.48 (95% CI, 0.28-0.83), respectively, after adjusting for age, sex, and family history of CRC. Conclusions: Increasing the frequency of colonoscopic intervention would have a risk reduction effect on interval cancers. Colonoscopic intervention twice or three times within the previous 5 years in the low-risk group and the increased-risk group had 67% and 52% risk reduction effects for prevalence of advanced adenoma, respectively.

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