Mo1581 Evaluation Method of Lesions in Small Bowel in Patients With Crohn's Disease With Preliminary Examination With Patency Capsule

Abstract

patients swallowed a PC. Diseased segments (DS) on the MRE were evaluated for the following imaging features: mean number of segments, stenosis and prestenotic dilatations, maximal stenosis length, maximal wall thickness and presence of enhancement.The association of these imaging features with the risk of PC retention was evaluated. Results: The radiologist gave a positive prediction of PC retention in 30/57 patients. Actual PC retention occurred in 13/57 patients and was predicted by MRE in 12/13 cases. The sensitivity, specificity, positive and negative predictive values (PPV/NPV) for prediction of PC retention were 92.3%, 59%, 40% and 96.3% respectively.Diseased segments were found in 45 /57 patients. The mean maximal stenosis length (9.7 cm vs 7 cm, pZ0.04) and the mean number of prestenotic dilatations (2 vs 1.1, pZ0.02) were significantly associated with PC retention. One case of symptomatic PC retention occurred in the study which resolved with steroid treatment. No cases of CE retention occurred. Conclusion: MRE has high NPV and sensitivity but low PPV and specificity for PC retention.Capsule retention suggested by MRE should not preclude performance of PC to determine the feasibility and safety of diagnostic CE. Longer stenosed strictures and higher number of prestenotic dilatations on MRE were significantly associated with PC retention.RE, SBH-equal contribution Funded by the Helmsley Charitable Fund