Abstract

In Japan, the colorectal cancer morbidity has been increasing year by year. Therefore, screening examination is essential for early detection of the colorectal cancer (CRC). Fecal occult blood test (FOBT) is a simple, low cost, non-invasive method. Furthermore, there has been firm experimental evidence that FOBT reduces the risk or CRC mortality. Therefore, FOBT is recommended as a population-based CRC screening in Japan. On the other hand, screening colonoscopy is considered as opportunistic screening based on a balance between benefits and disadvantages in spite of high-accuracy method.

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