Mo1542 Virtual Chromoendoscopy With I-Scan Enables More Precise Diagnosis of Mucosal Inflammation in Patients With Inflammatory Bowel Disease

Abstract

second in a 360-degree-panorama-view for the first 2 hours and 3fps for the rest of time. This enables a side view like with ERCP. A motion detector allows the video capsule to take photographs more frequently when the video capsule is moving more rapidly. The device does not employ wireless technology. SV1 saves the data on the on-board flash memory when it traverses through the bowel. The capsule is retrieved, opened by the docking station where the data are transferred by USB to the reviewing workstation. 19 patients (12 F and 7 M, mean age 42 y) in whom evaluation of the small bowel was indicated swallowed SV1 either after colonoscopy or after a preparation with 2 l of a PEG solution in the afternoon before the examination. The patients swallowed 20 mg of metoclopramide and 170 mg of simethicone 30 min before swallowing the capsule. They were allowed to eat after 6 hours. Results: The capsules were retrieved in 17 of 19 patients forming the study population. The indication was Crohn’s disease (after exclusion of stenoses) in 3, undefined chronic inflammatory disease in 1, NSAR use in 2, Anemia in 5, duodenal polyp after polypectomy in 1, chronic diarrhea in 2, tumor of unknown origin in 1, and unexplained abdominal discomfort in 2 patients. The mean time to pass the stomach was 26 min and the small bowel 243 min. The duodenal papilla was identified in 11 of 17 patients (65%). We further detected mucosal breaks/ulcers in 3 patients with Crohn’s disease, in 1 patient with NSAR use and in 1 patient with anemia. No adverse effects were detected. Discussion: Compared to capsules with cameras at the end, SV1 with a 360 degree imaging detects the duodenal papilla in a higher proportion which constitutes an advantage for the diagnosis of neoplasms of the papilla and duodenum. We also detected pathologic findings in the lower part of the small bowel. Every capsule reached the ileocecal valve. Small bowel capsule endoscopy with SV1 is a safe procedure. The panoramic imaging capsule seems to have an advantage in small bowel.