Abstract

the calculated index and Erythro-Sedimentation Rate (ESR) and C-Reactive Protein (CRP) expression. Correlation between the calculated index and the symptoms experienced by patients at the time of colonoscopy was assessed too. Finally, 50 videos of DD patients not involved in the development of DICA were reassessed in order to investigate the predictive role of DICA on the outcome of the disease. Results: A total of 960 ratings were performed by endoscopists involved. Overall agreement in using DICA was 0.847 (95% CI 0.812 to 0.893). It was 0.878 (95% CI 0.832 to 0.895) for DICA 1, 0.765 (95% CI 0.735 to 0.786) for DICA 2, and 0.891 (95% CI 0.845 to 0.7923) for DICA 3. Intra-observer agreement kappa was 0.91 (95% CI 0.886 to 0.947). A significant correlation was found between DICA score and both ESR (p=0.0001) and CRP values (p=0.0001), as well as between median pain score and DICA score (p=0.0001). With respect to the 50 patients retrospectively reassessed, recurrence or occurrence of disease complications were recorded in 29 (58%) patients: 10 (34.5%) were classified as DICA 1 and 19 (65.5%) as DICA 2 (p=0.036). Conclusions: Diverticular Inflammation and Complication Assessment (DICA) score is a simple, reproducible, validated, and easy-to-use endoscopic scoring system for diverticular disease of the colon.

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