Mo1174 Age Is a Predictor of Recurrent Gastrointestinal Bleeding in Patients With Left Ventricular Assist Devices: Results From an Urban Tertiary Care Center

Abstract

Background: Re-bleeding after initial hemostasis in peptic ulcer bleeding can be life threatening. Identifying factors associated with re-bleeding in patient with peptic ulcer bleeding is important. The aims of our study was to evaluate factors related with re-bleeding and to identify incidence rate of rebleeding in patients with high risk peptic ulcer bleeding. Method: Among patients diagnosed as upper gastrointestinal hemorrhage at seven hospitals in DaeguGyeongbuk, and one hospital in Gyeongnam, South korea, from Feb 2011 to Dec 2013, 699 patients diagnosed as high risk peptic ulcer bleeding with Forrest classification above llb were included. The data were obtained in a prospective manner. Results: Among 699 patients, 500 (71.5%) patients had gastric ulcer, 199 (28.5%), duodenal ulcer. Re-bleeding of high risk peptic ulcer occurred in 64 (9.2%) patients. Age, sex, ulcer type, Forrest classification and treatment modalities were not significantly different between re-bleeding and non-rebleeding group. Second look endoscopy was significantly more performed in non-rebleeding group than rebleeding group (81.8% vs 62.5%, P=<0.001). Transfusion volume was significantly higher in rebleeding group than non-rebleeding group (7.9 vs 3.1, p=<0.001). On multivariate analysis, performance of transfusion, larger transfusion volume and non-performance of second look endoscopy were found as risk factors for rebleeding in high risk peptic ulcer bleeding. Conclusion: In our study, incidence rate of rebleeding was 9.2% and non-performance of second look endoscopy, performance of transfusion and larger transfusion volume were found as risk factors for rebleeding in patients with high risk peptic ulcer bleeding.