Abstract

NCI has developed a number of research initiatives to help promote more standardized methods for the measurement of drug or therapy response using quantitative imaging. These initiatives include the following:1. PAR 07 214: (R01) Industry Academic Partnerships.2. PAR 08 225 (U01): Quantitative Imaging Network (QIN)3. RFA 08 225 (U54): Multi Modality Imaging Platforms4. SAIC Contracts: Data collections for RIDER projectThese initiatives involve the development of public resources for sharing image data and results of measurements that includes repeat and longitudinal measurements for phantom and clinical data for a range of imaging modalities (CT, PET CT, DCE MRI, DW MRI and optical imaging). This presentation will describe these resources and how they can be used to support more standardized quantitative imaging methods. In addition a review of recent juried consensus publications for how to use these NCI resources will be addressed. Finally NCI ongoing efforts to support the efforts of different imaging societies such as the RSNA (QIBA), AAPM, SNM and ISMRM will be presented.Learning Objectives1. Understand NCI initiatives for quantitative imaging2. Understand how to use the public resources to promote imaging standards3. Understand the importance of quantitative imaging as a biomarker for therapy related clinical trials.

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