MnFe2O4 nanoparticles-decorated graphene nanosheets used as an efficient peroxidase minic enable the electrochemical detection of hydrogen peroxide with a low detection limit

Abstract

Hydrogen peroxide (H2O2) is a common oxidant and major active oxygen species in organisms. There is a great requirement for the accurate and rapid determination of H2O2 in the fields of environmental analysis, clinical treatment, food safety, pharmaceuticals, etc. The electrochemical method is considered an ideal analytical technology due to its high sensitivity, fast response and low detection limit. Herein, a one-pot solvothermal synthesis method was used to prepare a manganese ferrite/reduced graphene oxide (MnFe2O4/rGO) composite, which was modified on the surface of home-made screen-printed electrodes to construct a new type of electrochemical sensor for the determination of H2O2, subsequently. Cyclic voltammetry and chronoamperometry were used to study the electrocatalytic performance of H2O2 reduction in neutral conditions. The results showed that the sensor had good electrocatalytic activity for the reduction of H2O2. The response time of the sensor is 5 s, and the linear detection range is 0.1 ~ 4.0 mM (R2 = 0.9991) with a low detection limit of 0.528 nM. Such sensor exhibited good long-term stability, and good anti-interfering ability from potential interfering species of glucose, ascorbic acid, dopamine, fructose and uric acid during the determination. This study thus provides a potential method to construct novel type of H2O2 for practical application.