Abstract
Cytomegalovirus is an opportunistic virus that can cause infection in any part of the gastrointestinal tract, mostly in immunocompromised patients and rarely in immunocompetent individuals. Cytomegalovirus infection almost always shows an aggressive course in immunocompromised patients, in contrary it is usually self-limited in immunocompetent individuals. But sometimes it produces severe manifestations in immunocompetent patients. Herein, we report a case of life-threatening cytomegalovirus colitis in an immunocompetent 79 year-old man. Cytomegalovirus colitis can be presented with clinical symptoms like abdominal pain, diarrhea, hematochezia, melena or fever. In endoscopic examination, ulceration, obstructive pseudomembrane formation, mucosal bleeding and/or inflammatory masses can be detected. Histopathologically, inflammatory processes ranging from minimal inflammation to deep ulcers or extensive necrosis can be observed in a wide spectrum. The characteristic histopathological feature is intranuclear or intracytoplasmic “owl’s eye” viral inclusions. A brief summary about cytomegalovirus infection in immunocompetent individuals and differential diagnosis are also given in this report.
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