Abstract

MLB1 Astrovirus in Children with Gastroenteritis, Italy

Highlights

  • Electron microscopy images of astrovirus-like particles in fecal samples from 2 patients in Italy: A) strain ITA/2007/PR326, from a 4-year-old child hospitalized in January 2007; and B) strain ITA/2008/PR3147, from a 14-month-old child hospitalized in November 2008

  • We hypothesized that the MLB1like astrovirus was the causative agent of the acute gastroenteric disease observed in the child, because this virus was the only infectious agent identified in samples from this patient

  • In a case–control study for MLB1-like astroviruses in India, no clear association was established between MLB1-like viruses and diarrhea, and no differences were observed in the viral load between symptomatic and asymptomatic subjects (9)

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Summary

Introduction

Electron microscopy images of astrovirus-like particles in fecal samples from 2 patients in Italy: A) strain ITA/2007/PR326, from a 4-year-old child hospitalized in January 2007; and B) strain ITA/2008/PR3147, from a 14-month-old child hospitalized in November 2008. In all the genome regions sequenced, the virus displayed the highest sequence identity to MLB1-like astroviruses (97.4%–98.2%). We hypothesized that the MLB1like astrovirus was the causative agent of the acute gastroenteric disease observed in the child, because this virus was the only infectious agent identified in samples from this patient.

Results
Conclusion
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