Abstract
Multiple myeloma is a neoplastic disorder caused by the proliferation of a single plasma cell clone and is associated with the production of monoclonal immunoglobulin. Multiple myeloma rarely involves the pleura, and this involvement indicates an unfavorable prognosis. We report a 53-year-old man with multiple myeloma and a myelomatous right-sided pleural effusion with elevated adenosine deaminase (ADA) activity. The diagnosis was made by examination of the pleural fluid cytology and pleural biopsy specimen. Systemic chemotherapy was administered to the patient, and pleuredesis was performed. However, the patient died 3.5 months after the diagnosis. Increased ADA activity may be observed in myelomatous pleural effusion, and it may mimic tuberculous pleuritis.
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