Mixing Technique of PMMA - Bone Cement Determines the Ideal Insertion Time Point in Cemented Arthroplasty

Abstract

1. Abstract 1.1. <span lang=EN-GB style=font-size:10.0pt; font-family: times= new= roman,serif;mso-ansi-language:en-gb=>Background: The aim of this study was to assess the influence of different mixing techniques on handling properties of PMMA-bone cement. 1.2. <span lang=EN-GB style=font-size:10.0pt; font-family: times= new= roman,serif;mso-ansi-language:en-gb=>Methods: Eighteen different mixing techniques which differ in mixing speed, use of vacuum, and storage temperature were performed and repeated five times. For each test group, the handling properties (doughing, working and setting time) were analysed. 1.3. <span lang=EN-GB style=font-size:10.0pt; font-family: times= new= roman,serif;mso-ansi-language:en-gb=>Results: Vacuum and temperature had a significant influence on the doughing, working and setting time (p<0.0001). Mixing speed had a significant effect on doughing time (p<0.0001). It was statistically calculated (two-way ANOVA) that the interaction between the use of vacuum and the mixing speed, and the interaction between temperature and the mixing speed had a significant influence on doughing time (p<0.0001). The interaction between temperature and mixing speed had a significant effect on setting time (p=0.0018). 1.4. <span lang=EN-GB style=font-size:10.0pt; font-family: times= new= roman,serif;mso-ansi-language:en-gb=>Conclusions: The mixing technique determines the viscosity of PMMA bone cement, thereby influencing the ideal time point for insertion. 2. Keywords: Bone Cement; Cemented Arthroplasty; Handling Properties; Mixing Speed; PMMA; Polymethylmethacrylate; Temperature; Vacuum