Abstract

Malignant transformation of mature cystic teratoma is uncommon, and occurs in approximately 2%–4% of cases [1]. The most common tumor is squamous cell carcinoma, followed by mucinous carcinoma, carcinoid tumor, thyroid carcinoma, etc.; however, any of the tissues in mature teratoma may undergo malignant transformation [1]. Goblet cell carcinoid (mucinous carcinoid) is a distinctive neoplasm with features of both carcinoid tumor and adenocarcinoma. Most cases described in the literature have occurred in the appendix and rarely, in the ovary. Although mature cystic teratomas occur in many extragonadal areas including the mesentery [2] and greater omentum, occurrence of goblet cell carcinoid arising in extragonadal teratoma has been rarely described, with only a single case in mediastinum being reported in the English literature [3]. Moreover, a combination of mucinous adenocarcinoma, goblet cell carcinoid, carcinoid tumor, and mature teratoma in an extragenital organ has not been reported. Herein, we present a rare case of combined mucinous adenocarcinoma and goblet cell and typical carcinoid tumor arising in mature cystic teratoma of the mesentery in a 48-year-old woman.

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