Abstract

Mitral valve repair for Barlow disease – long-term results

Highlights

  • Barlow disease is related to myxoid degeneration of all components of mitral valve apparatus [1]

  • Guidelines encourage referral of patients with Barlow disease to centers with surgeons experienced in mitral valve repair in order to achieve to decrease the number of replaced valves [8-10]

  • Forty- seven percent were in New York Heart Association (NYHA) functional class III or IV before surgery

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Summary

Introduction

Barlow disease is related to myxoid degeneration of all components of mitral valve apparatus [1]. At present mitral valve repair is considered the surgical gold standard: repair is more frequently associated with reverse left ventricular remodeling and restoration of left ventricular function in comparison to valve replacement. Guidelines encourage referral of patients with Barlow disease to centers with surgeons experienced in mitral valve repair in order to achieve to decrease the number of replaced valves [8-10]. Reconstructive surgery should be performed early in patients with severe mitral regurgitation (EROA ≥ 0.40 cm2) with reparable valves, before the occurrence of clinical symptoms, atrial fibrillation, pulmonary hypertension, and left ventricular dysfunction [11,12]. Present investigation reports 5-year follow-up results of mitral valve repair in 85 consecutive patients with Barlow disease underwent mitral valve repair at Heart surgery department of AOU Careggi.

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