Abstract

Three men with non-ischemic cardiomyopathy and heart failure (HF) underwent HeartMate II (Thoratec, Pleasanton, CA) left ventricular assist device (LVAD) placement as a bridge to heart transplantation. At baseline, all patients had severe LV dilatation, LV systolic dysfunction, and mitral annular dilatation, but no historical or echocardiographic evidence of mitral valve prolapse (MVP; Table 1). Mechanical unloading and reverse LV remodeling was achieved within 6 to 9 months of LVAD support in all patients, as evidenced by reductions in LV short-axis and long-axis dimensions, decreases in mitral annular diameter, and increases in LV ejection fraction (Table 1).

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