Abstract

Careful evaluation of patients with mitral stenosis has led the authors to differentiate a special type, to which the name of “mitral stenosis and cor pulmonale” has been given and which is characterized by the following points: (1) a history of pronounced respiratory symptoms; (2) an extreme degree of dyspnea; (3) electrocardiographic and roentgenographic evidence of marked right ventricular hypertrophy; (4) the early appearance of congestive heart failure; (5) marked alterations in circulatory dynamics with extremely high pressures n the pulmonary circulation. The pathogenesis of this “mitral stenosis and cor pulmonale” is marked by severe changes in the small pulmonary vessels of these patients. The clinical and physiologic differentiation of these patients is stressed.

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