Abstract

Two White Leghorn lines, HA and LA, which were developed by selection for high and low competences in graft-versus-host reaction (GVHR) and found to differ in resistance to Marek's disease, were compared for their responses to the mitogenic lectins in vitro. The numbers of peripheral blood lymphocytes were similar in both lines. The HA line showed higher incorporation of 3H-thymidine than the LA line, when they were stimulated with Con A and PHA. These results have suggested that the difference in response to the mitogens between the lines is attributed to their lymphoproliferative ability. Based on these findings, the relationship between resistance to MD and lymphoproliferative ability was discussed.

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