Abstract
1. 1. Large cytoplasmic organelles containing melanin granules (polymelanosomes) were centrifugally isolated from the melanocytes of the Amphiuma tridactylum liver. 2. 2. These polymelanosomes have significant amounts of the following enzyme activities: succinic oxidase, cytochrome oxidase and monoamine oxidase. 3. 3. The polymelanosomes also accumulate 54Mn similarly to mitochondria. 4. 4. It is concluded that these polymelanosomes have certain functional similarities to mitochondria.
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