Abstract
A study was undertaken on the effect of inhalation exposure of an acute dose of cadmium on mitochondrial enzymes in rat lungs. Citrate synthase, succinic dehydrogenase and cytochrome c oxidase were inhibited immediately after exposure and regained to near normal levels at the end of 336 hours. The cadmium level in the target tissue was not cleared effectively and the lung tissue showed histopathological changes such as focal thickening of alveolar septa with cuboidal cells lining alveoli.
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