Abstract
Mitochondria and Endoplasmic Reticulum in Diabetes and Its Complications
Highlights
In this special issue of the journal we have assembled several invited reviews, from well-recognized investigators, on the roles of mitochondrial dysfunction and endoplasmic reticulum (ER) stress in the pathogenesis of diabetes and its complications
Mitochondria are the most important source of the chemical energy required by cells
Regulation of the role that mitochondria play in the metabolism of glucose and fatty acids, the primary fuels used by cells to produce ATP, has been the subject of intensive research for several decades
Summary
In this special issue of the journal we have assembled several invited reviews, from well-recognized investigators, on the roles of mitochondrial dysfunction and ER stress in the pathogenesis of diabetes and its complications. Recent studies have provided evidence that mitochondrial dysfunction and endoplasmic reticulum (ER) stress are major pathogenic factors for diabetes and its complications. Mitochondria are the most important source of the chemical energy required by cells.
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