Abstract
Introduction: In Mali, the irrational use of drugs constitutes a public health problem through the misuse of certain psychotropic and / or analgesic drugs for drug addiction purposes. The aim of this study was to measure the consumption of drugs diverted from their therapeutic use in Bamako. Methods: This was a cross-sectional study carried out in Bamako with a sample of 260 respondents: 98 health workers and 162 clients (pharmacies) / patients (hospitals). Results: Men were more affected than women, with 62% of cases. The 15-45 age group accounted for 55% of cases. According to the results, workers and students respectively represented 19% and 17% of cases. Promethazine (20%), the combination Paracetamol / codeine / caffeine (13%) and Tramadol (11%) were the drugs most commonly used and diverted from their medical use among clients of pharmacies. According to pharmacists, the drugs affected by misuse were Misoprostol (10%), Clonazepam (9%) and Promethazine (9%). According to doctors and nurses, Misoprostol, Promethazine and diazepam were used for other purposes with 23%, 16% and 13%, respectively. Conclusion: In order to reduce this practice, a synergy of action by health professionals is essential for the rational use of drugs.
Highlights
In Mali, the irrational use of drugs constitutes a public health problem through the misuse of certain psychotropic and / or analgesic drugs for drug addiction purposes
Promethazine was (20%) of the drugs diverted from pharmacies while Tramadol (24%) was the most diverted molecule
We found that benzodiazepines followed by Antihistamines, Analgesics, Antidepressants and Antipeptic ulcer disease (Misoprostol) were the most widely used therapeutic classes in our study
Summary
In Mali, the irrational use of drugs constitutes a public health problem through the misuse of certain psychotropic and / or analgesic drugs for drug addiction purposes. The aim of this study was to measure the consumption of drugs diverted from their therapeutic use in Bamako. Promethazine (20%), the combination Paracetamol / codeine / caffeine (13%) and Tramadol (11%) were the drugs most commonly used and diverted from their medical use among clients of pharmacies. The drugs affected by misuse were Misoprostol (10%), Clonazepam (9%) and Promethazine (9%). In 2012, a study conducted at the Nancy University Hospital, pharmacists estimated that in 59.9% of cases, the request for Néo-Codion® was aimed at misuse [1]. The abuse of Tramadol for drug addiction (diverted use) has sharply increased in West Africa, in Mali, Niger and Burkina Faso [10]. In Bamako, in 1993, according to a study, 25% of adult women aged 15 to 45 used cosmetic products for artificial depigmenting and 69.8% admitted to having dermatological problems [11]
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