Abstract
Two types of dietary interventions; one based on the cholesterol hypothesis and another which recommended to reduce the intake of total fat energy, revealed no significant benefits for the prevention of CHD. One of future dietary intervention trials should include the followings.(1) Reducing the linoleic acid (ω6) intake from a current level of 7 energy % in the USA toward 3 energy %, the upper limit proposed by ISSFAL workshop10).(2) Increasing the intake of ω3 fatty acids toward 1.5 energy % (both 18 carbon and ≥20 carbon fatty acids roughly equally), a safe level that Japanese have experienced.(3) Minimizing the intakes of hydrogenated vegetable oils and the oils exhibiting anti-nutritional activities in animals. Animal fats are safer than these vegetable oils.
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