Abstract
ObjectiveTo look for another set of parameters to predict the change in infarct size in acute stroke patients with a perfusion-weighted imaging (PWI)–diffusion-weighted imaging (DWI) mismatch. Materials and MethodsWe reviewed 54 patients who had PWI-DWI mismatch and vascular occlusion on initial MRI and no recanalization of occluded vessel. ResultsTime-to-peak and time-to-max (TTP-Tmax) perfusion mismatch volume was independently significant as a correlate of infarct volume change (P=.004). ConclusionsThe finding of a large TTP-Tmax perfusion delay mismatch volume in patients with acute stroke who have a PWI-DWI mismatch on an initial MRI may predict that the infarct volume will not increase despite persistent vascular occlusion.
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