Abstract
Objective The objective of this review is to evaluate the usefulness of oral cobalamin (vitamin B12) treatment. Material and method PubMed was systematically searched for English and French articles published from January 1990 to January 2007. Results Prospective randomized studies ( n = 3), a systematic review by the Cochrane group ( n = 1) and prospective studies in well-determined population ( n = 5) provide evidence that oral cyanocobalamin therapy may adequately treat cobalamin deficiency in elderly patients. However, the current literature may not suggest a strategy in terms of the form (hydroxy- or cyanocobalamin), frequency and duration of the treatment. Conclusion This present review confirms the previously reported efficacy of oral cyanocobalamin treatment in elderly patients.
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