Abstract

Letters5 October 1999Misdiagnosis of HIV InfectionJosiah D. Rich, MD, MPH, Eleftherios Mylonakis, MD, and Timothy P. Flanigan, MDJosiah D. Rich, MD, MPHBrown University School of Medicine; Providence, RI 02906 (Rich)Brown University School of Medicine; Providence, RI 02906 (Mylonakis)Brown University School of Medicine; Providence, RI 02906 (Flanigan)Search for more papers by this author, Eleftherios Mylonakis, MDBrown University School of Medicine; Providence, RI 02906 (Rich)Brown University School of Medicine; Providence, RI 02906 (Mylonakis)Brown University School of Medicine; Providence, RI 02906 (Flanigan)Search for more papers by this author, and Timothy P. Flanigan, MDBrown University School of Medicine; Providence, RI 02906 (Rich)Brown University School of Medicine; Providence, RI 02906 (Mylonakis)Brown University School of Medicine; Providence, RI 02906 (Flanigan)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-131-7-199910050-00031 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Dr. Palmas suggests that different levels of diagnostic sensitivity (1) could help minimize false-positive results. Prospective studies can evaluate this issue and quantify the frequency of misdiagnosis of HIV infection by HIV-1 plasma viral load testing. In the meantime, physicians should use caution in diagnosing HIV infection solely on the basis of a detectable HIV-1 plasma viral load. However, we continue to encourage efforts to rapidly and accurately diagnose acute HIV infection. This is a responsibility for all care providers, not just specialists in the field.Goodman and colleagues describe the converse situation, in which an undetectable HIV-1 ...

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