Abstract
Misclassification of Bronchioloalveolar Carcinoma with Cytologic Diagnosis of Lung Cancer
Highlights
Cytology is commonly used to diagnose non-small cell lung cancer (NSCLC) but is an inaccurate means of diagnosis of bronchioloalveolar carcinoma (BAC)
Bronchioloalveolar carcinoma (BAC) is a subset of non-small cell lung cancer (NSCLC) associated with improved survival and distinct response to certain treatments compared with other subtypes of NSCLC.[1]
Existing evidence strongly suggests that mixed BAC predicts improved survival and has distinct genetic changes compared with pure adenocarcinoma.[2,3,4,5,6]
Summary
The aims of this study were to calculate the sensitivity and specificity of cytologic diagnosis of BAC and to estimate the misclassification of BAC as other subtypes of NSCLC
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