Abstract
Calcium pyrophosphate dihydrate deposition disease is a dis- ease characterized by collecting of crystals in hyaline carti- lage, fibrocartilage and soft tissues, related to many endo - crine and metabolic conditions, and seen more commonly in old age. Hypopituitarism may occur in old age with fatigue, decrease in libido, weight loss and musculoskeletal symptoms as a major cause of the overall condition impairment. As one gets older, the signs of these two diseases may progress even without any significant disease. The natural process which comes with old age, and pseudogout and hypopituitarism can mask one to another clinically and the symptoms of three situ- ation may be overlapping. This can lead to difficulty and delay in diagnosis. Our case was an elderly female patient diagnosed with hypopituitarism and pseudogout.
Highlights
While calcium pyrophosphate dihydrate deposition disease (CPDD), known as pseudogout is known to be coexistent with trauma, surgical operations, hemochromatosis, Wilson’s disease, hypophosphatasia, it is related to endocrine diseases, including hyperparathyroidism and hypothyroidism[1,2]
It is reported to be DISCUSSION Pseudogout is a disease characterized by acute, subacute or chronic inflammation as a result of accumula
In a retrospective study[11], it was reported that definitive diagnosis took 16.35 years in average, it was reported in the evaluation by Sanyal D. et al [10] that the diagnosis took 15.35 years in average
Summary
While calcium pyrophosphate dihydrate deposition disease (CPDD), known as pseudogout is known to be coexistent with trauma, surgical operations, hemochromatosis, Wilson’s disease, hypophosphatasia, it is related to endocrine diseases, including hyperparathyroidism and hypothyroidism[1,2]. Pseudogout can represent with various clinical manifestations such as acute, asymptomatic and pseudo-rheumatoid arthritis (pseudoRA). Various joints, the knees, are involved in a mono- or oligo-articular manner, and patients remain asymptomatic between attacks [3]. One of the diseases, which can be seen in old age, is hypopituitarism. With the diseases like polymyalgia rheumatica and rheumatoid arthritis (RA), which become more common in this age group, the differential diagnosis between these diseases and pseudogout becomes difficult. The natural process which comes with old age, and pseudogout and hypopituitarism can mask one to another clinically. We want to share a 69-year old patient, whom we diagnosed with pseudogout accompanied with hypopituitarism and arthritis at intervals
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