Mirex and behavior in the Long-Evans rat.

Abstract

In two experiments, adult male Long-Evans rats were fed chow containing mirex (1.78 ppm and 17.8 ppm in Experiment 1, 17.8 ppm in Experiment 2) over a several week period and were tested on a variety of behavioral tasks. No differences in behavior were seen between control and experimental animals tested in an open-field apparatus, on VI 30-sec and DRL 20-sec operant paradigms, or on a discrimination-reversal task motivated by escape from footshock.