Abstract

SummaryWe present Mirage 2.0, which accurately estimates gene-content evolutionary history by considering heterogeneous evolutionary patterns among gene families. Notably, we introduce a deterministic pattern mixture model, which makes Mirage substantially faster and more memory-efficient to be applicable to large datasets with thousands of genomes.Availability and implementationThe source code is freely available at https://github.com/fukunagatsu/Mirage.Supplementary information Supplementary data are available at Bioinformatics online.

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