Abstract
Background Estrogen receptor (ER) status has been used as a biomarker in breast carcinomas (BC), allowing the identification of tumors that may respond to ER antagonists or aromatase inhibitors. Two previous studies by our group evaluating gene and miRNA expression profiles in BC samples from Brazilian patients revealed 15 genes and 3 microRNAs as significantly associated with BC, according to ER status. The aim of this study was to evaluate the correlation between these 3 microRNAs and ER-related genes in BC.
Highlights
Estrogen receptor (ER) status has been used as a biomarker in breast carcinomas (BC), allowing the identification of tumors that may respond to ER antagonists or aromatase inhibitors
Two previous studies by our group evaluating gene and miRNA expression profiles in BC samples from Brazilian patients revealed 15 genes and 3 microRNAs as significantly associated with BC, according to ER status
C. Camargo Cancer Treatment and Research Center, São Paulo, SP, Brazil
Summary
The aim of this study was to evaluate the correlation between these 3 microRNAs and ER-related genes in BC
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