Abstract
Edvardas Vaicekavičius, Virgilijus Grinius, Ramūnas Navickas, Ramūnas Unikas, Arnoldas JanavičiusKaunas University of Medicine, Institute of CardiologyE-mail: invlab@kmu.lt Background / objective Reperfusion may limit the amount of potentially salvageable ischemic but viable myocardium due to reperfusion damage and injury. The objective of this study was to compare primary percutaneous transluminal coronary angioplasty (PTCA) with stenting according myocardial reperfusion quality in early hospital period. Methods One hundred nineteen patients presenting with acute myocardial infarction < 12 hours were treated by primary PTCA or stenting (n = 26). PTCA patients (n = 93) were divided in to 1st group (n = 75) of survived and 2nd group (n = 18) of died patients. Stented patients consisted 3rd gr. (n = 26). The main indications for stenting after angioplasty were: 1) significant (type D, E, or F) dissection of coronary arteries, 2) significant elastic recoil. Peri-procedural TIMI flow, resolution of ST elevation and evolution of ECG stages were used for assessment of reperfusion quality. QRS score and left ventricle EF were used for assessment of LV function. Results The highest TIMI flow, the most intensive resolution of ST, the evolution of ECG stages and the lowest QRS score were noticed for 3rd gr. of stented patients. The died patients (2nd gr.) had lower TIMI flow (p = 0,097472), higher ST (p = 0,0073) and lower EF (p = 0,0005) in comparing with the 1st gr. of patients. Conclusions The procedural in-hospital outcome demonstrate that coronary stenting can be used as the primary modality for patients undergoing coronary interventions for acute myocardial infarction, increasing TIMI flow myocardial, reducing reperfusion damage and infarct size. Keywords: myocardial infarct reperfusion, myocardial infarct size, primary percutaneous transluminal coronary angioplasty and stenting.
Highlights
Miokardo reperfuzija gali sumaþinti potencialiai gyvybingo iðeminio miokardo plotà dël galimo reperfuzinio paþeidimo ir reperfuzijos neadekvatumo
Iðvados Stacionaro rezultatai parodë, kad skubus vainikiniø arterijø (VA) stentavimas turëtø bûti pirmo pasirinkimo metodas sergant ûminiu ST elevacinio miokardo infarkto (STEMI), nes labiau pagerina rekanalizuotos arterijos kraujotakà, sumaþina reperfuziná paþeidimà ir reperfuzijos neadekvatumà, dël to iðvengiama vëlesniø komplikacijø
One hundred nineteen patients presenting with acute myocardial infarction < 12 hours were treated by primary percutaneous transluminal coronary angioplasty (PTCA) or stenting (n = 26)
Summary
Miokardo reperfuzija gali sumaþinti potencialiai gyvybingo iðeminio miokardo plotà dël galimo reperfuzinio paþeidimo ir reperfuzijos neadekvatumo. Ðio darbo tikslas buvo nustatyti miokardo reperfuzijos (MR) ankstyvuosius skirtumus, gautus po skubios pirminës perkutaninës transliuminës vainikiniø arterijø angioplastikos (PTVAA) arba stentavimo sergant ûminiu miokardo infarktu su ST tarpo pakilimu (STEMI). Analizavome duomenis 119 ligoniø, suskirstytø á dvi grupes – ligoniø, kuriems atlikta PTVAA ir stentavimas. Treèià grupæ (n = 26) sudarë ligoniai, kuriems atliktas vainikiniø arterijø (VA) stentavimas. Periprocedûrinë TIMI tëkmë, ST pakilimo normalizacija, MI EKG stadijø evoliucija, QRS balø suma ir kairiojo skilvelio iðvaromoji frakcija (KSIF) buvo panaudota miokardo reperfuzijai ir funkcijai ávertinti. Kuriems atliktas VA stentavimas, buvo nustatyta intensyviausia TIMI tëkmë, EKG stadijø evoliucija ir ΣST↑ normalizacija bei maþiausia QRS balø suma, palyginti su pirmos grupës ligoniais. Pagrindiniai þodþiai: miokardo infarkto zonos reperfuzija, pirminë perkutaninë transliuminali vainikiniø arterijø angioplastika ir stentavimas, miokardo infarkto plotas. The objective of this study was to compare primary percutaneous transluminal coronary angioplasty (PTCA) with stenting according myocardial reperfusion quality in early hospital period
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
