Abstract

Micro-electrode dot array (MEDA) biochips are widely used due to dynamical control of the droplets in microfluidic manipulations. MEDA allows microelectrodes cells to transport droplets of different sizes for operations. For concurrent manipulation of multiple droplets, each droplet is initially placed at a distant position to avoid undesirable mixing, and the droplets travel a long way for the operations. In this paper, we propose a droplet routing method to minimize routing area in MEDA biochips, considering splitting of droplets during routing. Experiments demonstrate that our proposal can achieve a reduction in routing area compared to the state-of-the-art method.

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