Abstract
Minimal deviation adenocarcinoma (MDA) of the uterine cervix is a rare disease. The rate of misdiagnosis is relatively high and there is no standard treatment. A 58-year-old woman presented with an abnormal Pap smear revealing atypical glandular cells and vaginal mucoid discharge. Cervical biopsy revealed cervicitis and an endometrium with atypical glands and increasing mitoses. A frozen section of curetted endometrial tissue revealed adenocarcinoma. Surgical staging with laparoscopic hysterectomy, bilateral salpingo-oophorectomy, and bilateral pelvic lymph node dissection was then performed. However, uterine cervical MDA was confirmed by pathology and immunohistochemistry with carcinoembryonic antigen and vimentin. Because the staging surgery was inadequate (the parametrium was not radically resected), postoperative adjuvant therapy with concurrent chemoradiation was performed. The patient remained disease-free as of the last follow-up 6 months postoperatively. MDA is difficult to diagnose and depends on its clinical manifestations and pathologic features. Surgery with adjuvant chemoradiotherapy achieves good outcomes.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
