Abstract
The HeartMate 3 Left Ventricular Assist system (LVAS) has demonstrated enhanced hemocompatibility, with absence of de-novo pump thrombosis. However, clinically observed bleeding-related adverse events continue to remain significantly burdensome. We hypothesized that the enhanced hemocompatibility of the HeartMate 3 LVAS allows the safe use of decreased anticoagulation intensity, potentially decreasing bleeding-related adverse events.
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