Abstract

Horseshoe crabs have been identified as one of the marine species that contribute greatly to scientific advances especially in haematological studies. Besides the haemocytes of these creatures, they are also well known for their protein contents in the perivitelline fluid (PVF). Due to this, over the years, there has been increasing interests in the scientific community to explore the function of proteins in the PVF of horseshoe crab for applications in various biomedical areas such as immunology, embryology and tissue or cell engineering. This article will review the two main protein components found in the PVF of the horseshoe crab namely, lectins, and hemocyanins with regards to its applications in medical research.

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