Abstract
We have developed a brief screening test aimed at identifying cognitive disorders in Parkinson’s disease. The Mini-Mental Parkinson derives from the Mini-Mental State Examination of Folstein. It includes seven ordered subsections, with a total score of 32. A pilot study was conducted in 50 community-dwelling parkinsonian patients, in order to establish its metrological qualities. Comparisons were made with a neuropsychological battery including several tests widely used in the assessment of specific cognitive disorders in Parkinson’s disease. The correlations between the Mini-Mental Parkinson and each component of this battery were substantial, especially for the performance subtests of the WAIS-R (r= 0.62 to 0.72), the Stroop test (r= 0.65) the 15-objects test (r= 0.64), the word fluency (r= 0.63) and the Odd Man Out test (r= 0.61). The validity of each subtest of the Mini-Mental Parkinson was adequate except for one, based on a word choice, which requires a modification in French before definitive use. The test-retest reliability was high (r= 0.84). There was a significant difference in the mean scores in cases with confusional event (22.4), even without current signs of dementia, compared with patients with no such history (27.2). In conclusion, this brief test is suitable for assessment of parkinsonian patients.
Highlights
Cognitive disorders in Parkinson's disease (PD) have been studied extensively in recent years
We have developed a short bedside test, the Mini-Mental Parkinson (MMP), designed to assess the cognitive disorders in PD, and aimed at identifying those patients requiring in-depth assessment
The MMP total score correlated with each component of the neuropsychological battery
Summary
Cognitive disorders in Parkinson's disease (PD) have been studied extensively in recent years (for reviews, see Brown and Marsden, 1991; Guillard et al, 1991; Dubois et al, 1991). In Alzheimer's disease and related disorders, bedside tests such as the Mini-Mental State (MMS) (Folstein et al, 1975) and Information Memory Concentration test (Blessed et al, 1968) have been adopted, making it possible to compare data from different studies, to perform long-term longitudinal studies on large populations and to screen well-defined population samples for therapeutic trials. These short tests are especially helpful when patients cannot. In particular there are two steps for cognitive disorders in PD: first, early "subtle" cognitive troubles, qualitatively and quantitatively quite different from DAT impairment; second, it may inconstantly appear dementia
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